Poly Cystic Ovary Syndrome-Hormonal Disease in Female

 Poly Cystic Ovary Syndrome-Hormonal Disease in Female


Poly cystic ovary syndrome (PCOS) is a hormonal disease common among women of reproductive era. Women with PCOS issue may have light or heavy menstrual periods or excess male hormone that is called androgen. It makes the ovaries to produce follicles which fails to release the eggs regularly. The main reason of polycystic syndrome is unknown. Early diagnosis and treatment with weight loss may lessen the risk of prolong issues such as type 2 diabetes and heart disease.


Signs and symptoms of PCOS may develop gradually at the time of the first menstrual period during adolescence. Sometimes PCOS develops after sometimes, for example, in response to some weight gain. Signs and symptoms of PCOS may be different. A diagnosis of PCOS is made when you experience at least 2 or 3 of these signs:

  1. Irregular Periods In PCOS: Infrequent, irregular, or long-time menstrual cycles are the most usual sign of PCOS.
  2. Excess Androgen: Excess levels of male hormones may result in physical signs, such as excess facial and body hair (hirsutism), and usually severe acne and male-pattern baldness occurs.
  3. Poly Cystic Ovaries: Your ovaries might be large and contain follicles that occupied the eggs.

Cause of Poly Cystic Ovary Syndrome

  • Excessive Insulin

Insulin is the hormone produced in the pancreas that allows cells to utilize sugar, your body’s primary power supply. Excess insulin may increase androgen making, causing problem with ovulation.

  • Low-Grade Inflammation

It is used to describe WBC production of that fight against infection. Studies have shown that women with PCOS have a type of low-grade inflammation that promotes poly cystic ovaries to produce androgen.

  • Heredity

Studies suggests that certain genes may be linked to PCOS.

  • Excess Androgen 

The ovaries produce high levels of androgen that are not normal, resulting in hirsutism and acne and other problems.


  • Infertility issues
  • Diabetes or pregnancy-induced high BP
  • Miscarriage issues
  • Liver inflammation caused by fat deposition in the liver.
  • Sleep apnea disorder
  • Depression, anxiety and eating disorders or stress related issues.
  • Abnormal uterine bleeding or heavy periods
  • Cancer of the uterus


There is no test to accurate diagnose PCOS. Your doctor is likely to start with a discussion of your health and previous medical history, including your menstrual periods and weight changes. A physical examination will be done checking for signs of excess hair growth, insulin resistance and acne. Your doctor may then recommend you for:

A Pelvic Exam

The doctor visually and inspects by hands your reproductive organs for masses, growths or other issues that are except than normal.

Blood Tests

Your blood sample can be taken to check hormone levels.

An Ultrasound

Your doctor checks the shape of your ovaries and the thickness of the lining of your uterus. By use of a wand like device (transducer) is inserted in your vagina (transvaginal ultrasound). The transducer has sound waves that are translated into images on a computer screen. If you have a diagnosis of PCOS, your doctor may recommend some extra tests for complications including:

  • Periodic examination of blood pressure, glucose tolerance, and cholesterol and triglyceride levels
  • Stain out for depression and anxiety.
  • Stain out for obstructive sleep apnea disorder.


PCOS treatment concentrates on maintain your personal issues, such as infertility, hirsutism, acne, or obesity. Specific treatment may include lifestyle changes or medication.

Lifestyle Changes

Your doctor may recommend weight loss by having a low-calorie diet combined with moderate exercise activities.


To normalize your menstrual cycle, your doctor may suggest medications which includes:

  • Combination Birth Control Pills 

Supplements that have estrogen and progestin lessens androgen production and normalize estrogen. normalizing your hormones can reduce your risk of endometrial cancer and correct abnormal bleeding, excess hair growth and acne. Moreover, these supplements decrease androgen production that can cause excessive hair growth.

  • Progestin Therapy

Taking progestin for 10 to 14 days every one to two months can normalize your menses and protect against endometrial cancer. Progestin therapy does not better androgen levels and will not prevent pregnancy. To aid you ovulate, your doctor might suggest:

  • Clomiphene 

This is an oral anti-estrogen medication take during the first phase of your menstrual cycle.

  • Letrozole (Femara) 

This breast cancer medication can work to regulate the ovaries.

  • Metformin

This oral medication for type 2 diabetes betters insulin resistance and lowers insulin levels.

  • Gonadotropins 

These hormone medications are injected insides you.


To lessens excessive hair growth, your doctor may recommend you an electrolysis in which a small needle pin is penetrating each hair follicle. The needle ejects a pulse of electric current to damage and eventually destruct the follicle.

Lifestyle and Home Remedies

To aids to decrease the effects of PCOS, try to:

  1. Maintain a healthy weight- Weight loss can lessen insulin and androgen levels and may restore ovulation. Ask your care giver or consultant about a weight-control program and meet on appointment with a dietitian for help in reaching weight-loss goals.
  2. Limit carbohydrates– Low-fat, high-carbohydrate diets may increase insulin levels.
  3. Be active– Exercise aids in lower blood sugar levels. If you have PCOS, increasing your daily activity and take part in a regular exercise program may treat or even prevent insulin resistance.

Preparing for Your Appointment

You may have to go to a specialist in female reproductive medicine (gynecologist), a specialist in hormone disorders (endocrinologist) or an infertility specialist (reproductive endocrinologist).

  • List symptoms and issues you have been having, and for how long.
  • Write down all medications, vitamins and supplements you take, including the doses take all the files with you.
  • List recent life changes and stressors
  • Prepare questions to ask your consultant.

What You Should Ask to Your Doctor?

  • What tests do you suggest?
  • How does PCOS affect my ability to conceive?
  • What medicines do you recommend helping me in bettering my symptoms or ability to conceive?
  • What lifestyle modifications do you suggest helping improve my symptoms or ability to conceive?

Expectations from Your Doctor

  • Your doctor must ask you several questions, including:
  • What are your signs and symptoms? How often do they occur?
  • How severe are your symptoms you are facing now?
  • When did each symptom begin?
  • When was your last menses?
  • Have you gain weight when you have your first menses? How much weight do you gain now, and when did you gain it before this?
  • Does anything make better or worse your symptoms?
  • Are you trying to become pregnant, or do you wish to conceive?
  • Have you the family history of PCOS?



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